Detalhe da pesquisa
1.
Mucus-degrading Bacteroides link carbapenems to aggravated graft-versus-host disease.
Cell
; 185(20): 3705-3719.e14, 2022 09 29.
Artigo
Inglês
| MEDLINE | ID: mdl-36179667
2.
Structure of a B12-dependent radical SAM enzyme in carbapenem biosynthesis.
Nature
; 602(7896): 343-348, 2022 02.
Artigo
Inglês
| MEDLINE | ID: mdl-35110734
3.
Streptothricin F is a bactericidal antibiotic effective against highly drug-resistant gram-negative bacteria that interacts with the 30S subunit of the 70S ribosome.
PLoS Biol
; 21(5): e3002091, 2023 05.
Artigo
Inglês
| MEDLINE | ID: mdl-37192172
4.
A conserved zinc-binding site in Acinetobacter baumannii PBP2 required for elongasome-directed bacterial cell shape.
Proc Natl Acad Sci U S A
; 120(8): e2215237120, 2023 02 21.
Artigo
Inglês
| MEDLINE | ID: mdl-36787358
5.
High efficacy of the F-ATP synthase inhibitor TBAJ-5307 against nontuberculous mycobacteria in vitro and in vivo.
J Biol Chem
; 300(2): 105618, 2024 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-38176652
6.
Oral Tebipenem Pivoxil Hydrobromide in Complicated Urinary Tract Infection.
N Engl J Med
; 386(14): 1327-1338, 2022 04 07.
Artigo
Inglês
| MEDLINE | ID: mdl-35388666
7.
Global distribution and genomic characteristics of carbapenemase-producing Escherichia coli among humans, 2005-2023.
Drug Resist Updat
; 72: 101031, 2024 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-38071860
8.
ThnL, a B12-dependent radical S-adenosylmethionine enzyme, catalyzes thioether bond formation in carbapenem biosynthesis.
Proc Natl Acad Sci U S A
; 119(34): e2206494119, 2022 08 23.
Artigo
Inglês
| MEDLINE | ID: mdl-35969793
9.
Recurrent emergence of Klebsiella pneumoniae carbapenem resistance mediated by an inhibitory ompK36 mRNA secondary structure.
Proc Natl Acad Sci U S A
; 119(38): e2203593119, 2022 09 20.
Artigo
Inglês
| MEDLINE | ID: mdl-36095213
10.
Interactions of hydrolyzed ß-lactams with the L1 metallo-ß-lactamase: Crystallography supports stereoselective binding of cephem/carbapenem products.
J Biol Chem
; 299(5): 104606, 2023 05.
Artigo
Inglês
| MEDLINE | ID: mdl-36924941
11.
Individualized Antibiotic Plans as a Quality Improvement Initiative to Reduce Carbapenem Use for Hematopoietic Cell Transplant Patients at a Freestanding Pediatric Hospital.
Clin Infect Dis
; 78(1): 15-23, 2024 Jan 25.
Artigo
Inglês
| MEDLINE | ID: mdl-37647637
12.
Identifying Effective Durations of Antibiotic Therapy for the Treatment of Carbapenem-resistant Enterobacterales Bloodstream Infections: A Multicenter Observational Study.
Clin Infect Dis
; 78(1): 27-30, 2024 Jan 25.
Artigo
Inglês
| MEDLINE | ID: mdl-37584360
13.
Clinical Outcomes and Bacterial Characteristics of Carbapenem-resistant Acinetobacter baumannii Among Patients From Different Global Regions.
Clin Infect Dis
; 78(2): 248-258, 2024 Feb 17.
Artigo
Inglês
| MEDLINE | ID: mdl-37738153
14.
A preliminary exploration on the mechanism of the carbapenem-resistance transformation of Serratia marcescens in vivo.
BMC Genomics
; 25(1): 2, 2024 Jan 02.
Artigo
Inglês
| MEDLINE | ID: mdl-38166565
15.
Respiratory carriage of hypervirulent Klebsiella pneumoniae by indigenous populations of Malaysia.
BMC Genomics
; 25(1): 381, 2024 Apr 17.
Artigo
Inglês
| MEDLINE | ID: mdl-38632538
16.
Clinical isolates of Streptococcus mitis/oralis-related species with reduced carbapenem susceptibility, harboring amino acid substitutions in penicillin-binding proteins in Japan.
Antimicrob Agents Chemother
; 68(4): e0117923, 2024 Apr 03.
Artigo
Inglês
| MEDLINE | ID: mdl-38415648
17.
Simulated drug disposition in critically ill patients to evaluate effective PK/PD targets for combating Pseudomonas aeruginosa resistance to meropenem.
Antimicrob Agents Chemother
; 68(3): e0154123, 2024 Mar 06.
Artigo
Inglês
| MEDLINE | ID: mdl-38319075
18.
A multi-species outbreak of VIM-producing carbapenem-resistant bacteria in a burn unit and subsequent investigation of rapid development of cefiderocol resistance.
Antimicrob Agents Chemother
; 68(4): e0150723, 2024 Apr 03.
Artigo
Inglês
| MEDLINE | ID: mdl-38376188
19.
I n vitro pharmacokinetics/pharmacodynamics of the ß-lactamase inhibitor, durlobactam, in combination with sulbactam against Acinetobacter baumannii-calcoaceticus complex.
Antimicrob Agents Chemother
; 68(1): e0031223, 2024 Jan 10.
Artigo
Inglês
| MEDLINE | ID: mdl-38092676
20.
Escherichia coli sequence type 410 with carbapenemases: a paradigm shift within E. coli toward multidrug resistance.
Antimicrob Agents Chemother
; 68(2): e0133923, 2024 Feb 07.
Artigo
Inglês
| MEDLINE | ID: mdl-38193668